![Melatonin restricts the viability and angiogenesis of vascular endothelial cells by suppressing HIF-1α/ROS/VEGF Melatonin restricts the viability and angiogenesis of vascular endothelial cells by suppressing HIF-1α/ROS/VEGF](https://www.spandidos-publications.com/article_images/ijmm/43/2/IJMM-43-02-0945-g07.jpg)
Melatonin restricts the viability and angiogenesis of vascular endothelial cells by suppressing HIF-1α/ROS/VEGF
![MicroRNAs and the HIF/VEGF axis in ocular neovascular diseases - Plastino - 2021 - Acta Ophthalmologica - Wiley Online Library MicroRNAs and the HIF/VEGF axis in ocular neovascular diseases - Plastino - 2021 - Acta Ophthalmologica - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/a8cbefa0-4ef7-4ef2-b17b-12ec8888d615/aos14845-fig-0001-m.jpg)
MicroRNAs and the HIF/VEGF axis in ocular neovascular diseases - Plastino - 2021 - Acta Ophthalmologica - Wiley Online Library
![Frontiers | Safranal Inhibits Angiogenesis via Targeting HIF-1α/VEGF Machinery: In Vitro and Ex Vivo Insights Frontiers | Safranal Inhibits Angiogenesis via Targeting HIF-1α/VEGF Machinery: In Vitro and Ex Vivo Insights](https://www.frontiersin.org/files/Articles/789172/fonc-11-789172-HTML/image_m/fonc-11-789172-g006.jpg)
Frontiers | Safranal Inhibits Angiogenesis via Targeting HIF-1α/VEGF Machinery: In Vitro and Ex Vivo Insights
![Regulation of redox signaling in HIF‐1‐dependent tumor angiogenesis - Manuelli - 2022 - The FEBS Journal - Wiley Online Library Regulation of redox signaling in HIF‐1‐dependent tumor angiogenesis - Manuelli - 2022 - The FEBS Journal - Wiley Online Library](https://febs.onlinelibrary.wiley.com/cms/asset/e9bdd539-0719-4dbf-b1f8-42562f357c33/febs16110-fig-0002-m.jpg)
Regulation of redox signaling in HIF‐1‐dependent tumor angiogenesis - Manuelli - 2022 - The FEBS Journal - Wiley Online Library
![IJMS | Free Full-Text | Repair Mechanisms of the Neurovascular Unit after Ischemic Stroke with a Focus on VEGF IJMS | Free Full-Text | Repair Mechanisms of the Neurovascular Unit after Ischemic Stroke with a Focus on VEGF](https://www.mdpi.com/ijms/ijms-22-08543/article_deploy/html/images/ijms-22-08543-g001.png)
IJMS | Free Full-Text | Repair Mechanisms of the Neurovascular Unit after Ischemic Stroke with a Focus on VEGF
![Mechanism and Consequences of The Impaired Hif-1α Response to Hypoxia in Human Proximal Tubular HK-2 Cells Exposed to High Glucose | Scientific Reports Mechanism and Consequences of The Impaired Hif-1α Response to Hypoxia in Human Proximal Tubular HK-2 Cells Exposed to High Glucose | Scientific Reports](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41598-019-52310-6/MediaObjects/41598_2019_52310_Fig9_HTML.png)
Mechanism and Consequences of The Impaired Hif-1α Response to Hypoxia in Human Proximal Tubular HK-2 Cells Exposed to High Glucose | Scientific Reports
Impairment of hypoxia-induced angiogenesis by LDL involves a HIF-centered signaling network linking inflammatory TNFα and angiogenic VEGF - Figure f3 | Aging
![PSF functions as a repressor of hypoxia-induced angiogenesis by promoting mitochondrial function | Cell Communication and Signaling | Full Text PSF functions as a repressor of hypoxia-induced angiogenesis by promoting mitochondrial function | Cell Communication and Signaling | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12964-020-00684-w/MediaObjects/12964_2020_684_Figa_HTML.png)
PSF functions as a repressor of hypoxia-induced angiogenesis by promoting mitochondrial function | Cell Communication and Signaling | Full Text
![Upregulation of HIF-1α induce angiogenesis through VEGF in hypoxia. 4... | Download Scientific Diagram Upregulation of HIF-1α induce angiogenesis through VEGF in hypoxia. 4... | Download Scientific Diagram](https://www.researchgate.net/publication/315967583/figure/fig2/AS:482476297592833@1492042721882/Upregulation-of-HIF-1a-induce-angiogenesis-through-VEGF-in-hypoxia-4-Adapted-with.png)
Upregulation of HIF-1α induce angiogenesis through VEGF in hypoxia. 4... | Download Scientific Diagram
![Hypoxia Triggers Osteochondrogenic Differentiation of Vascular Smooth Muscle Cells in an HIF-1 (Hypoxia-Inducible Factor 1)–Dependent and Reactive Oxygen Species–Dependent Manner | Arteriosclerosis, Thrombosis, and Vascular Biology Hypoxia Triggers Osteochondrogenic Differentiation of Vascular Smooth Muscle Cells in an HIF-1 (Hypoxia-Inducible Factor 1)–Dependent and Reactive Oxygen Species–Dependent Manner | Arteriosclerosis, Thrombosis, and Vascular Biology](https://www.ahajournals.org/cms/asset/8c53d731-1d61-41ff-94df-6e6a5b993199/1088ga1.jpg)
Hypoxia Triggers Osteochondrogenic Differentiation of Vascular Smooth Muscle Cells in an HIF-1 (Hypoxia-Inducible Factor 1)–Dependent and Reactive Oxygen Species–Dependent Manner | Arteriosclerosis, Thrombosis, and Vascular Biology
![ESMO 2021: Phase 2 Study of Belzutifan (MK-6482), an Oral Hypoxia-Inducible Factor 2α (HIF-2α) Inhibitor, Plus Cabozantinib for Treatment of Advanced Clear Cell Renal Cell Carcinoma (ccRCC) ESMO 2021: Phase 2 Study of Belzutifan (MK-6482), an Oral Hypoxia-Inducible Factor 2α (HIF-2α) Inhibitor, Plus Cabozantinib for Treatment of Advanced Clear Cell Renal Cell Carcinoma (ccRCC)](https://www.urotoday.com/images/com-doc-importer/18-esmo-2021/esmo-2021-phase-2-study-of-belzutifan-mk-6482-an-oral-hypoxia-inducible-factor-2-hif-2-inhibitor-plus-cabozantinib-for-treatment-of-advanced-clear-cell-renal-cell-carcinoma-ccrcc/image-0.jpg)
ESMO 2021: Phase 2 Study of Belzutifan (MK-6482), an Oral Hypoxia-Inducible Factor 2α (HIF-2α) Inhibitor, Plus Cabozantinib for Treatment of Advanced Clear Cell Renal Cell Carcinoma (ccRCC)
![Dysregulation of HIF and VEGF is a unifying feature of the familial hamartoma syndromes: Cancer Cell Dysregulation of HIF and VEGF is a unifying feature of the familial hamartoma syndromes: Cancer Cell](https://www.cell.com/cms/attachment/3239dd58-b3c0-4bb4-8b11-72440ff4004f/gr1_lrg.jpg)
Dysregulation of HIF and VEGF is a unifying feature of the familial hamartoma syndromes: Cancer Cell
![Inhibition of the hypoxia-inducible factor pathway by a G-quadruplex binding small molecule | Scientific Reports Inhibition of the hypoxia-inducible factor pathway by a G-quadruplex binding small molecule | Scientific Reports](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fsrep02799/MediaObjects/41598_2013_Article_BFsrep02799_Fig1_HTML.jpg)
Inhibition of the hypoxia-inducible factor pathway by a G-quadruplex binding small molecule | Scientific Reports
![Targeting hypoxia-inducible factor 1 (HIF-1) signaling with natural products toward cancer chemotherapy | The Journal of Antibiotics Targeting hypoxia-inducible factor 1 (HIF-1) signaling with natural products toward cancer chemotherapy | The Journal of Antibiotics](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41429-021-00451-0/MediaObjects/41429_2021_451_Fig1_HTML.png)